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DecisionRx to offer free PGx testing for Humana PathWays members in Indiana

10 hours ago
By AI, Created 13:00 UTC, Oct 27, 2026, AGP -

DecisionRx and Humana Healthy Horizons in Indiana are launching no-cost pharmacogenomic testing and pharmacist-led medication optimization for eligible PathWays for Aging members. The program aims to cut medication failure and avoidable spending for Indiana dual-eligible patients.

Why it matters: - Indiana dual-eligible members in Humana’s PathWays for Aging program will get access to personalized prescribing support at no cost. - The collaboration targets medication failure, a major driver of avoidable spending and adverse drug events in older adults. - DecisionRx cites independent analyses showing more than 30% reductions in annualized healthcare costs per engaged patient.

What happened: - DecisionRx announced a collaboration with Humana Healthy Horizons in Indiana to provide free pharmacogenomic testing and pharmacist-led medication optimization for eligible PathWays for Aging members. - Qualifying members will be invited to complete a one-time PGx test at no cost. - DecisionRx clinical pharmacists will review each member’s PGx results, medication list, claims history and clinical context. - Pharmacists will send personalized prescribing recommendations directly to the member’s prescriber for consideration. - The service is offered at no additional cost to participants.

The details: - Humana’s Fully Integrated Dual Eligible and Medicaid PathWays members in Indiana are eligible for the program. - The process starts with at-home DNA collection kits and enrollment information sent to eligible members. - Participation is voluntary. - DecisionRx pharmacists will develop medication action proposals using a patented medication risk assessment format. - Patients and prescribers will consult through a secure telemedicine platform. - Pharmacogenomic results are expected to remain clinically relevant for the patient’s lifetime and may inform future prescribing decisions across providers. - DecisionRx’s platform combines pharmacogenomic data, pharmacist review and prescription analytics in one workflow. - The system is designed to identify drug-gene interactions, drug-drug contraindications and other opportunities to optimize therapy. - The prescribing physician keeps full clinical authority over any medication changes. - Research cited by DecisionRx says about 40% of prescriptions are ineffective or create new clinical issues. - The same research says medication failure accounts for an estimated 16% of total U.S. healthcare spending. - The company says adverse drug events hit older adults especially hard because many take five or more prescriptions at once. - A Health Affairs Scholar study of more than 15,000 Medicare beneficiaries found the DecisionRx program was associated with a 31.9% reduction in medical spending, equal to $462 PMPM. - Anna Dunn, president of Humana Healthy Horizons in Indiana, said the partnership is meant to make personalized, preventive care part of the PathWays experience. - Travis Morgan, president and co-founder of DecisionRx, said Indiana’s dual-eligible population deserves prescribing guided by genetics and clinical history rather than population averages.

Between the lines: - The partnership fits a broader push toward precision medicine in value-based care. - Humana gets a lower-cost support layer for a high-need population with heavy medication use. - DecisionRx gets a larger real-world channel to show that pharmacist-led medication therapy optimization can reduce spending and improve prescribing quality. - The model shifts part of the prescribing workflow upstream, before drug trial-and-error leads to complications.

What's next: - Eligible members will receive enrollment materials and at-home DNA kits. - DecisionRx pharmacists will begin reviewing results and contacting prescribers after members enroll. - The companies did not provide a start date for member outreach or specify how many Indiana members will be included. - Future prescribing decisions may incorporate the PGx results across providers because the test data remain clinically relevant over time.

The bottom line: - Humana and DecisionRx are pairing free genetic testing with pharmacist review to try to make medication choices safer, faster and less costly for Indiana PathWays members.

Disclaimer: This article was produced by AGP Wire with the assistance of artificial intelligence based on original source content and has been refined to improve clarity, structure, and readability. This content is provided on an “as is” basis. While care has been taken in its preparation, it may contain inaccuracies or omissions, and readers should consult the original source and independently verify key information where appropriate. This content is for informational purposes only and does not constitute legal, financial, investment, or other professional advice.

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